Health

Mapping the Hope Attractor: A Conversation with Thomas- Homer Dixon

In this conversation, Thomas Homer-Dixon introduces the Cascade Institute’s Polycrisis Core Model (PCM), a novel framework designed to map and analyse interactions among 11 critical global systems, each with multiple potential future states. The model employs cross-impact balance (CIB) analysis to evaluate over four million internally consistent scenarios, ultimately identifying 11 distinct “attractor” states. These […]

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Tackling the Complex Links Between Climate Change, Conflict, and Health

The authors underscore the urgent need to address the interconnected threats of climate change, conflict, and health. They highlight how these threats not only cause direct harm, such as heat-related deaths and conflict-driven mortality, but also compound vulnerabilities by damaging health systems, disrupting essential services, and fueling cycles of instability. Fragile and conflict-affected states are

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Spatial Mobility Under Crisis: Policy Responses and Migration Dynamics in Five Countries

The authors examine how public health crises have reshaped migration governance and spatial mobility. Focusing on the Netherlands, the United Kingdom, China, Brazil, and Ghana, the study analyzes policy responses and their implications for migration dynamics. The findings suggest that national responses were shaped by factors such as epidemic trajectories, economic conditions, healthcare systems, political

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Global Systemic Stresses: Understanding the Drivers of Polycrisis

This report introduces the Cascade Institute’s Stress-Trigger-Crisis model, a systemic framework that distinguishes between slow-moving stresses that erode the resilience of global systems and fast-moving trigger events that precipitate crises. It identifies 14 global systemic stresses that affect nine vital systems: climate, ecology, food, energy, economy, infrastructure, health, social order and governance, and world order.

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Global Health at a Crossroads: WHO’s 2025 Emergency Response to Outbreaks, Conflicts and Humanitarian Crises

The author examines how 2025 has become a pivotal year for global health, marked by converging crises such as conflict, disease outbreaks, climate shocks, and displacement that are impacting fragile health systems and exposing deep structural inequities. In response, the WHO’s $1.5 billion Health Emergency Appeal underscores the urgency of coordinated, resilient action, emphasizing mobile

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Exploring the Intersection between Artificial Intelligence and Biological Sciences: Focus on Uses and Challenges

This report examines how artificial intelligence is transforming biosafety, biosecurity, biodefense, and global health, while simultaneously introducing new biological risks. Drawing on a systematic review of 169 scientific articles and surveys of life science professionals across Latin America, it finds that AI tools are increasingly applied to epidemiological prediction, protein design, and laboratory automation, yet

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The Impact of Polycrisis on Healthcare Systems—Analyzing Challenges and the Role of Social Epidemiology

This article examines how overlapping global crises are converging to form a polycrisis that places unprecedented strain on healthcare systems worldwide. Applying social epidemiology to the analysis of polycrisis, the authors highlight how these interconnected threats amplify one another, exposing systemic vulnerabilities and deepening health inequities. Drawing on data from missed hospitalizations, conflict zones such

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Managing and Mitigating Future Public Health Risks: Planetary Boundaries, Global Catastrophic Risk, and Inclusive Wealth

The authors argue for a more integrated framework to understand existential risks by bridging two dominant paradigms: Planetary Boundaries and Global Catastrophic Risks. Using the COVID-19 pandemic as a case study, the authors analyze how pandemics reveal the interconnectedness of public health, environmental degradation, and global systems. They critique the fragmentation between the Planetary Boundaries

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Pathogens and planetary change

The authors examine the interconnected crises of emerging infectious diseases, biodiversity loss, and environmental change, highlighting their growing social and ecological costs. They explore how pathogens respond to global change and its implications for pandemic prevention and biodiversity conservation, emphasizing the need for targeted strategies such as pathogen surveillance, conservation interventions, and stronger health systems.

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